Administration: Intravenous injection is preferred. Intracardiac injection may be made when intravenous injection is impractical, as in a very small dog, or hinein a comatose dog with impaired vascular functions. Good injection skill is necessary for intracardiac injection.
Abuse of pentobarbital can cause dependence and addiction and lead to overdose. In case of overdose immediately seek medical help or contact Poison Control.
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The use of a Luer-Eisenbahn® syringe is recommended to prevent accidental exposure due to needle/syringe separation.
Barbiturates are capable of producing all levels of CNS mood alteration from excitation to mild sedation, to hypnosis, and deep coma. Overdosage can produce death. Rein high enough therapeutic doses, barbiturates induce anesthesia.
For intravenous injection, a needle of sufficient gauge to ensure intravenous placement of the entire dose should be used. The use of a Luer-Bahn® syringe is recommended to prevent accidental exposure to needle/syringe separation.
Use with caution rein patients with respiratory disease. Intubation may be required before treatment for seizures or traumatic brain injury.
Barbiturates are respiratory depressants. The degree of respiratory depression is dependent upon dose. With hypnotic doses, respiratory depression produced by barbiturates is similar to that which occurs during physiologic sleep with slight decrease rein blood pressure and heart Satz.
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Although the clinical literature abounds with claims that the short-acting barbiturates are superior for producing sleep while the intermediate-acting compounds are more effective rein maintaining sleep, controlled studies have more info failed to demonstrate these differential effects. Therefore, as sleep medications, the barbiturates are of limited value beyond short-term use.
No adequate well-controlled studies have been conducted rein pediatric patients; however, safety and effectiveness of pentobarbital in pediatric patients is supported by numerous studies and case reports cited rein the literature.
Each ingredient acts in such a manner so as to cause humane, painless, and rapid euthanasia. Euthanasia is due to cerebral death hinein conjunction with respiratory arrest and circulatory collapse. Cerebral death occurs prior to cessation of cardiac activity.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
pentobarbital will decrease the level or effect of lorlatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.